EUがワクチン輸出の承認義務付け WHOは「囲い込み」懸念<新型コロナ>
河野太郎行政改革担当相は29日、「ワクチンをEUから日本に輸入することを考えていた」と述べ、EUからの輸出規制とも取れる動きに懸念を表明した
東京新聞 TOKYO Web tokyo-np.co.jp/article/83086
The P.1 variant #COVID19 has so far only been identified in Brazil, and in travellers from Brazil reported in Japan and South Korea. ecdc.europa.eu/en/publication…
This risk assessment presents the latest available information on the recent emergence of three variants of concern, VOC 202012/01 identified in the United Kingdom (UK), 501Y.V2 identified in South Africa, and P.1 identified in Brazil and Japan.
ecdc.europa.eu/en/publication…@ECDC_EUpic.twitter.com/WC9nniqCAD
Helpful Moderna slide showing the differences between UK variant (B.1.1.7) and South Africa variant (B.1.351).
B.1.351 (as well as variant called P.1 in Brazil/Japan) have the more troubling mutation on the receptor-binding domain of the spike protein. Specifically E484K. pic.twitter.com/NxsItPfduz
What you need to know about the coronavirus variants:
Original variant (D614G)
Denmark variant (L452R)
UK variant (B.1.1.7)
Brazil variant (P. 1)
South Africa variant (B1.351)
washingtonpost.com/health/interac…
.@TheLancet27Jan2021: "four non-mutually exclusive possible explanations for resurgence of COVID19 in Manaus" are discussed. Data from coronavirus variants P.1 & P.2 found in Brazil show April peak, period of possible #HerdImmunity, then rapid resurgence.
thelancet.com/journals/lance…
So the race is becoming more dynamic:
1. Vaccinations which work well vs D614G (wild-type) and B.1.1.7, amping up
2. Spread and immune escape of B.1.351 and P.1
3. Spread of B.1.1.7
4. Potential emergence of even more fit variants, now that we have entered more rapid evolution
@HarrySpoelstra@firefoxx66@AineTooleHarry, thx for passing this along - appreciate it greatly. From my understanding of the article (via google translate), variant P.2 was detected in NL but variant P.1 was not?
Is this your reading of it as well?
Let me know if I am missing something
@mridulkthomas@CovidVariants
メモ
新型コロナウイルス感染における「ニューロピリン1」(NRP1)の役割について
この今月1月4日発表の論文かな?
「The role of Neuropilin-1 in COVID-19」
journals.plos.org/plospathogens/…
シグナル伝達タンパク質のひとつ。
in vitroでは、新型コロナウイルスの感染力を増強。
嗅球から中枢神経系への拡散